Familial Idiopathic Pulmonary Fibrosis (FIPF): A Comprehensive Review

Authors

DOI:

https://doi.org/10.63908/4ma9rt51

Keywords:

Familial Idiopathic Pulmonary Fibrosis (FIPF), Idiopathic Pulmonary Fibrosis (IPF), Genetic, Surfactant-Related Gene Mutations, Telomere-Related Gene Mutations

Abstract

Familial Idiopathic Pulmonary Fibrosis (FIPF) is a subset of idiopathic pulmonary fibrosis (IPF) characterized by familial clustering, affecting multiple relatives across generations. While most IPF cases are sporadic, FIPF accounts for approximately 5–20% of cases and is linked to genetic mutations that predispose individuals to the disease. This review provides a comprehensive overview of FIPF, focusing on its genetic basis, clinical manifestations, diagnostic approaches, and therapeutic strategies. It also highlights recent research findings and future directions in the field.

Author Biography

  • Abdulrahman Hakami, Department of Medicine, college of medicine, Jazan university, Jazan, Saudi Arabia

    Department of Medicine, college of medicine, Jazan university, Jazan, Saudi Arabia

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Published

2025-10-30

Data Availability Statement

The data presented in this study are available on request from the corresponding author. 

Issue

Vol. 1 No. 3 & 4 (2025): The Saudi Journal of Health Research and Practice

Section

Articles

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Copyright (c) 2025 Saudi Journal of Health Research & Practice

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This work is licensed under a Creative Commons Attribution 4.0 International License.